5th Period Hot Spot (五時間目のホット·スポット, Go Jikan Me no Hotto Supotto) is the twelfth and final episode of the anime series Full Metal Panic? Fumoffu.
A classmate accidentally opens Sousuke's bio-hazardous container, causing a classroom quarantine. Sousuke later learns that the contents were not pathogenic, but destroys synthetic clothing instead. Relieved that there is no outbreak, he now fears the repercussions from his angry classmates.